(4R)-1-甲基-4-(1-甲基乙烯)-2-环己烯-1-醇合成路线 （共 5 条）
反应条件
boron trifluoride diethyl etherate; sodium hydrogencarbonate; magnesium sulfate
参考文献
Journal of the American Chemical Society, , vol. 129, # 12 p. 3698 - 3702
反应条件
1: 37.5 percent / MgSO4; BF3*Et2O / CH2Cl2 / 2.5 h / 0 °C 2: 47 percent / LiAlH4 / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 48, # 23 p. 7389 - 7399
反应条件
1: (4R)-1-methyl-4-(1-methylvinyl)cyclohex-2-en-1-ol in dichloromethane 1 h; 2: 5-(1-pentyl)resorcinol With zinc(II) chloride in dichloromethane; water T=0 - 40°C; 0.833333 h;
参考文献
EURO-CELTIQUE S.A.
Patent: WO2006/133941 A2, 2006 ;
Location in patent: Page/Page column 80-81 ;
反应条件
1: With sodium tetrahydroborate; diphenyl diselenide in ethanol
2 h; Heating;
2: With dihydrogen peroxide in tetrahydrofuran
2 h; Heating;
参考文献
PRESIDENT AND FELLOWS OF HARVARD COLLEGE; RITTER, Tobias; FURUYA, Takeru; TANG, Pingping
Patent: WO2010/59943 A2, 2010 ;
Location in patent: Page/Page column 69;70 ;
反应条件
1: With C48H42N2O4S5 in acetonitrile
0.5 h; Irradiation;
2: With sodium tetrahydroborate in ethanol
T=0°C; Darkness;
3: With water in ethanol
参考文献
Rapozzi, Valentina; Beverina, Luca; Salice, Patrizio; Pagani, Giorgio A.; Camerin, Monica; Xodo, Luigi E.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 5 p. 2188 - 2196
