3,4,5-三甲氧基苯甲醛合成路线 （共 427 条）
反应条件
sodium hydroxide in water
Claisen-Schmidt Condensation; Microwave irradiation;
参考文献
Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.
European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131
反应条件
1: benzene
2: Raney nickel; ethanol / 100 °C / 73550.8 Torr / Hydrogenation
View Scheme
参考文献
Adorni; Ishii
Anales de la Asociacion Quimica Argentina (1921-2001), 1945 , vol. 33, p. 71,75
反应条件
sodium tetrahydroborate
1.) methanol, dioxane, 20 min, r.t.; 2.) methanol, dioxane, 20 min, 0 deg C; Yield given. Multistep reaction;
参考文献
Simig; Fetter; Hornyak; et al.
Acta Chimica Hungarica, 1985 , vol. 119, # 1 p. 17 - 32
反应条件
1: 90 percent / K2CO3 / H2O / 4 h / 70 °C
2: 64 percent / Br2 / CHCl3 / 1 h / 0 °C
3: 56 percent / KOH / H2O; ethanol / 8 h / Heating
View Scheme
参考文献
Tanoguchi, Mariko; Kashima, Tatsuhiko; Saika, Hideyuki; Inoue, Taishi; Arimoto, Masao; Yamaguchi, Hideo
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 1 p. 68 - 72
反应条件
1: N2H4*H2O, KOH, triethylene glycol
2: POCl3
3: AlCl3
4: Zn-Hg, aq. HCl / toluene
5: (KO3S)2NO, aq. NaOAc
View Scheme
参考文献
Aquila,H.
Justus Liebigs Annalen der Chemie, 1969 , vol. 721, p. 220 - 222
反应条件
sodium acetate in acetic acid
参考文献
Campaigne,E.; Kreighbaum,W.E.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1326 - 1327
反应条件
in dimethyl sulfoxide
Wittig reaction; 0.0833333 h; Irradiation;
参考文献
Frattini, Sara; Quai, Monica; Cereda, Enzo
Tetrahedron Letters, 2001 , vol. 42, # 39 p. 6827 - 6829
反应条件
1: acetic acid / Heating
2: 95 percent / zinc dust; acetic acid / 20 °C
View Scheme
参考文献
Jursic, Branko S.; Stevens, Edwin D.
Tetrahedron Letters, 2003 , vol. 44, # 10 p. 2203 - 2210
反应条件
1: (i) P(OEt)3, (ii) /BRN= 395163/, NaOMe
2: H2 / PtO2
View Scheme
参考文献
Drewes,S.E.; Fletcher,I.P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1974 , p. 961 - 962
反应条件
in toluene
T=90°C; 8 h; Inert atmosphereMolecular sieve; diastereoselective reaction;
参考文献
Wu, Xingxing; Li, Lei; Zhang, Junliang
Chemical Communications, 2011 , vol. 47, # 27 p. 7824 - 7826
