N,N-二甲基-1-萘胺合成路线 （共 67 条）
反应条件
potassium fluoride; 18-crown-6 ether; ammonium hydrogen carbonate in tetrahydrofuran T=60°C; 12 h; Inert atmosphere;
参考文献
Bhojgude, Sachin Suresh; Kaicharla, Trinadh; Biju, Akkattu T.
Organic Letters, 2013 , vol. 15, # 21 p. 5452 - 5455
参考文献
Bamberger; Helwig
Chemische Berichte, 1889 , vol. 22, p. 1315
反应条件
trimethylsilylazide; iodosylbenzene in tetrahydrofuran T=0°C; 0.166667 h;
参考文献
Magnus, Philip; Lacour, Jerome; Weber, Wolfgang
Synthesis, 1998 , # SPEC. ISS. APR. p. 547 - 551
反应条件
titanium tetrachloride in dichloromethane T=0 - 25°C; 5.5 h;
参考文献
Periasamy, Mariappan; Kishorebabu, Neela; Natarajan Jayakumar
Tetrahedron Letters, 2007 , vol. 48, # 11 p. 1955 - 1958
反应条件
trichlorophosphate in toluene T=30 - 80°C; Vilsmeier reaction; 2 h;
参考文献
Vinogradova; Filatova; Vistorobskii; Pozharskii; Borovlev; Starikova
Russian Journal of Organic Chemistry, 2006 , vol. 42, # 3 p. 338 - 348
反应条件
hydrogenchloride; formaldehyd; 4-hydroxyl-amino-toluene-sulfonic acid-(2)
参考文献
Guinot, Stephane G. R.; Hepworth, John D.; Wainwright, Mark
Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 2 p. 297 - 303
反应条件
1: 1-N,N-dimethylaminonaphthalene With n-butyllithium in diethyl ether T=20°C; 48 h; 2: With N,N-dimethyl-formamide in diethyl ether T=-60°C; 1 h; 3: methanol in diethyl ether T=-20°C; 3 h;
参考文献
Foeldi, Agota Anna; Ludanyi, Krisztina; Benyei, Attila Csaba; Matyus, Peter
Synlett, 2010 , # 14 art. no. G13310ST, p. 2109 - 2113
反应条件
n-butyllithium 1.) ether, room temp., 48 h; 2.) ether, -78 deg C up to -20 deg C within 4 h; Yield given. Multistep reaction;
参考文献
Kirby, Anthony J.; O'Carroll, Fiona
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1994 , # 4 p. 649 - 656
反应条件
pyridine in chloroform 18 h; Ambient temperature;
参考文献
Okada, Etsuji; Masuda, Ryoichi; Hojo, Masaru; Tomifuji, Takeshi
Heterocycles, 1993 , vol. 36, # 4 p. 845 - 856
反应条件
2: 1.) NaH / 1.) THF, reflux, 18 h; 2.) reflux, 1 h
View Scheme
参考文献
Kirby, Anthony J.; Percy, Jonathan M.
Tetrahedron, 1988 , vol. 44, # 22 p. 6903 - 6910
