sodium acetate in water 0.5 h;

1: 97 percent / acetic acid; acetic anhydride / 4 h / Ambient temperature 2: 96 percent / lithium aluminum hydride / diethyl ether / 2 h / Heating 3: 100 percent / diethyl ether; pyridine / 2 h / Heating 4: PPA, phosphorus pentoxide / toluene / 24 h / Heating 5: 85 percent / ammonia / ethane-1,2-diol; ethanol / Ambient temperature; overnight 6: 81 percent / borane/dimethyl sulfide / tetrahydrofuran / 4 h / Heating 7: 82 percent / sodium acetate / H2O / 1 h / Ambient temperature View Scheme

1: 100 percent / diethyl ether; pyridine / 2 h / Heating 2: PPA, phosphorus pentoxide / toluene / 24 h / Heating 3: 85 percent / ammonia / ethane-1,2-diol; ethanol / Ambient temperature; overnight 4: 81 percent / borane/dimethyl sulfide / tetrahydrofuran / 4 h / Heating 5: 82 percent / sodium acetate / H2O / 1 h / Ambient temperature View Scheme

1: 96 percent / lithium aluminum hydride / diethyl ether / 2 h / Heating 2: 100 percent / diethyl ether; pyridine / 2 h / Heating 3: PPA, phosphorus pentoxide / toluene / 24 h / Heating 4: 85 percent / ammonia / ethane-1,2-diol; ethanol / Ambient temperature; overnight 5: 81 percent / borane/dimethyl sulfide / tetrahydrofuran / 4 h / Heating 6: 82 percent / sodium acetate / H2O / 1 h / Ambient temperature View Scheme

1: PPA, phosphorus pentoxide / toluene / 24 h / Heating 2: 85 percent / ammonia / ethane-1,2-diol; ethanol / Ambient temperature; overnight 3: 81 percent / borane/dimethyl sulfide / tetrahydrofuran / 4 h / Heating 4: 82 percent / sodium acetate / H2O / 1 h / Ambient temperature View Scheme

1: 88 percent / ZnCl2, 85percent H3PO4 / toluene / Heating 2: 60 percent / t-butyl hypochlorite / benzene; CHCl3 / 1) 0 deg C, 2 h, 2) r.t., overnight 3: 94 percent / conc. HCl / tetrahydrofuran; H2O / 2 h / Heating 4: 77 percent / ammoniumacetate, / acetic acid; benzene / 30 h / Heating 5: 73 percent / NaOH / H2O / 0.17 h / 65 °C 6: 87 percent / iodine / ethanol / 24 h / Heating 7: 49 percent / Cu powder / quinoline / 1 h / 180 °C 8: 54 percent / pyridine / 3 h / Heating 9: 1) benzoyl peroxide, NBS / 1) CCl4, reflux, 10 h, 2) DMSO 10: 81 percent / K2CO3 / acetone / 18 h / Heating 11: 1) borane/dimethyl sulfide, 2) 1.0 M HCl / 1) THF, 45 min, reflux, 2) CH3OH, reflux 12: 87 percent / sodium acetate / H2O / 0.5 h View Scheme

1: 77 percent / ammoniumacetate, / acetic acid; benzene / 30 h / Heating 2: 73 percent / NaOH / H2O / 0.17 h / 65 °C 3: 87 percent / iodine / ethanol / 24 h / Heating 4: 49 percent / Cu powder / quinoline / 1 h / 180 °C 5: 54 percent / pyridine / 3 h / Heating 6: 1) benzoyl peroxide, NBS / 1) CCl4, reflux, 10 h, 2) DMSO 7: 81 percent / K2CO3 / acetone / 18 h / Heating 8: 1) borane/dimethyl sulfide, 2) 1.0 M HCl / 1) THF, 45 min, reflux, 2) CH3OH, reflux 9: 87 percent / sodium acetate / H2O / 0.5 h View Scheme

1: 60 percent / t-butyl hypochlorite / benzene; CHCl3 / 1) 0 deg C, 2 h, 2) r.t., overnight 2: 94 percent / conc. HCl / tetrahydrofuran; H2O / 2 h / Heating 3: 77 percent / ammoniumacetate, / acetic acid; benzene / 30 h / Heating 4: 73 percent / NaOH / H2O / 0.17 h / 65 °C 5: 87 percent / iodine / ethanol / 24 h / Heating 6: 49 percent / Cu powder / quinoline / 1 h / 180 °C 7: 54 percent / pyridine / 3 h / Heating 8: 1) benzoyl peroxide, NBS / 1) CCl4, reflux, 10 h, 2) DMSO 9: 81 percent / K2CO3 / acetone / 18 h / Heating 10: 1) borane/dimethyl sulfide, 2) 1.0 M HCl / 1) THF, 45 min, reflux, 2) CH3OH, reflux 11: 87 percent / sodium acetate / H2O / 0.5 h View Scheme

1: 87 percent / iodine / ethanol / 24 h / Heating 2: 49 percent / Cu powder / quinoline / 1 h / 180 °C 3: 54 percent / pyridine / 3 h / Heating 4: 1) benzoyl peroxide, NBS / 1) CCl4, reflux, 10 h, 2) DMSO 5: 81 percent / K2CO3 / acetone / 18 h / Heating 6: 1) borane/dimethyl sulfide, 2) 1.0 M HCl / 1) THF, 45 min, reflux, 2) CH3OH, reflux 7: 87 percent / sodium acetate / H2O / 0.5 h View Scheme

1: 94 percent / conc. HCl / tetrahydrofuran; H2O / 2 h / Heating 2: 77 percent / ammoniumacetate, / acetic acid; benzene / 30 h / Heating 3: 73 percent / NaOH / H2O / 0.17 h / 65 °C 4: 87 percent / iodine / ethanol / 24 h / Heating 5: 49 percent / Cu powder / quinoline / 1 h / 180 °C 6: 54 percent / pyridine / 3 h / Heating 7: 1) benzoyl peroxide, NBS / 1) CCl4, reflux, 10 h, 2) DMSO 8: 81 percent / K2CO3 / acetone / 18 h / Heating 9: 1) borane/dimethyl sulfide, 2) 1.0 M HCl / 1) THF, 45 min, reflux, 2) CH3OH, reflux 10: 87 percent / sodium acetate / H2O / 0.5 h View Scheme