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结构式
乙二醇
甲醛
63148-62-9
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二甲基亚砜
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857259-65-5
合成路线
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857259-65-5
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反应条件
37928-17-9
5-甲基-3,4-二苯基-异噁唑
反应条件
hydrogenchloride in water T=40 - 102°C; 2 - 21.5 h; Heating / reflux; Product distribution / selectivity;
参考文献
Dr. Reddy's Laboratories Ltd.; Dr. Reddy's Laboratories, Inc.
Patent: EP1550658 A1, 2005 ;
Location in patent: Page/Page column 6; 8 ;
857259-65-5
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反应条件
181696-35-5
伐地考昔杂质D
反应条件
1: hydrogenchloride / water / 98 - 102 °C / Large scale reaction 2: chlorosulfonic acid / dichloromethane / 0 °C / Reflux 3: water / tetrahydrofuran / 24 h / Reflux View Scheme
参考文献
Reddy, Anumula Raghupathi; Goverdhan, Gilla; Sampath, Aalla; Mukkanti, Khagga; Reddy, Padi Pratap; Bandichhor, Rakeshwar
Synthetic Communications, 2012 , vol. 42, # 5 p. 639 - 649
857259-65-5
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反应条件
181695-72-7
伐地考昔
反应条件
1.1: hydrogenchloride / water / 98 - 102 °C / Large scale reaction 2.1: chlorosulfonic acid / dichloromethane / 0 °C / Reflux 2.2: 1 h / 25 - 35 °C View Scheme
参考文献
Reddy, Anumula Raghupathi; Goverdhan, Gilla; Sampath, Aalla; Mukkanti, Khagga; Reddy, Padi Pratap; Bandichhor, Rakeshwar
Synthetic Communications, 2012 , vol. 42, # 5 p. 639 - 649
857259-65-5
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反应条件
509074-26-4
4-(5-甲基-3-苯基异噁唑-4-基)苯磺酰氯
反应条件
1: hydrogenchloride / water / 98 - 102 °C / Large scale reaction 2: chlorosulfonic acid / dichloromethane / 0 °C / Reflux View Scheme
参考文献
Reddy, Anumula Raghupathi; Goverdhan, Gilla; Sampath, Aalla; Mukkanti, Khagga; Reddy, Padi Pratap; Bandichhor, Rakeshwar
Synthetic Communications, 2012 , vol. 42, # 5 p. 639 - 649