2,3,5-三氟-4-丙基三联苯合成路线 （共 3 条）
反应条件
potassium carbonate; bis-triphenylphosphine-palladium(II) chloride in Solmix A-11
T=60 - 65°C; Inert atmosphereReflux;
参考文献
Chisso Corporation; Chisso Petrochemical Corporation
Patent: EP2123623 A1, 2009 ;
Location in patent: Page/Page column 47-48 ;
反应条件
potassium carbonate; palladium on activated charcoal in Solmix A-11; water; toluene
3 h; RefluxInert atmosphere;
参考文献
CHISSO PETROCHEMICAL CORPORATION; JNC CORPORATION
Patent: US2012/29194 A1, 2012 ;
Location in patent: Page/Page column 30-31 ;
反应条件
1.1: sec.-butyllithium / cyclohexane; hexane; tetrahydrofuran / 3 h / -74 - -65 °C / Inert atmosphere
1.2: 1 h / -75 - -68 °C
2.1: potassium carbonate / palladium on activated charcoal / toluene; water; Solmix A-11 / 3 h / Reflux; Inert atmosphere
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参考文献
CHISSO PETROCHEMICAL CORPORATION; JNC CORPORATION
Patent: US2012/29194 A1, 2012 ;
