5-烯丙基-3-甲氧基水杨酸甲酯合成路线 （共 8 条）
参考文献
Bishop; Mathis; Gerdes; Whitney; Eaton; Mailman
Journal of Medicinal Chemistry, 1991 , vol. 34, # 5 p. 1612 - 1624
反应条件
1: 92 percent / 18 M H2SO4 / 58 h / Heating 2: 93 percent / K2CO3 / acetone / 12 h / Heating 3: 92 percent / 0.75 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 5 p. 1612 - 1624
反应条件
1: 93 percent / K2CO3 / acetone / 12 h / Heating 2: 92 percent / 0.75 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 5 p. 1612 - 1624
反应条件
lithium aluminium tetrahydride in diethyl ether 4 h; Heating;
参考文献
Pal, Gautam; Venkateswaran, Ramanathapuram V.
Journal of Chemical Research - Part S, 2003 , # 3 p. 142 - 143
反应条件
1: methanol; KOH-solution 2: dimethylaniline / 160 °C View Scheme
参考文献
Claisen
Justus Liebigs Annalen der Chemie, 1919 , vol. 418, p. 102
参考文献
Claisen
Justus Liebigs Annalen der Chemie, 1919 , vol. 418, p. 102
反应条件
1: potassium hydroxide / 220 - 235 °C 2: ethyl acetate; ozone / anschliessende Hydrierung an Palladium/Kohle View Scheme
参考文献
Freudenberg; Klink
Chemische Berichte, 1940 , vol. 73, p. 1369,1372
反应条件
1.1: 96 percent / sodium hydride / tetrahydrofuran / 2.5 h / 0 - 20 °C
2.1: BH3 / tetrahydrofuran / 1.5 h / 0 - 20 °C
2.2: 63 percent / hydrogen peroxide; NaOH / tetrahydrofuran; H2O / 1.5 h / 0 - 20 °C
3.1: 94 percent / pyridine / CH2Cl2 / 20 °C
4.1: 77 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 2 h / 55 - 60 °C
5.1: 100 percent / aq. NaOH / tetrahydrofuran / 1 h / 80 °C
6.1: 50 percent / trifluoroacetic acid / CH2Cl2
View Scheme
参考文献
Mukherjee, Jogeshwar; Shi, Bingzhi; Christian, Bradley T.; Chattopadhyay, Sankha; Narayanan, Tanjore K.
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 1 p. 95 - 102
