1: aq. NaOH, tetrabutylammonium hydrogensulfate / CH2Cl2 / 72 h / 65 °C 2: 77 percent / liq. NH3, sodium / tetrahydrofuran / 1.) -78 deg C, 1 h, 2.) reflux, 45 min 3: 51 percent / 10-camphorsulfonic acid / methanol View Scheme

1: sodium hydride / tetrahydrofuran / Reflux 2: hydrogenchloride / methanol; dichloromethane / Reflux View Scheme

1: sodium hydride / tetrahydrofuran / Reflux 2: hydrogenchloride / methanol; dichloromethane / Reflux 3: sodium hydride / tetrahydrofuran / Reflux 4: hydrogenchloride / methanol; dichloromethane / Reflux View Scheme

1: sodium hydride / tetrahydrofuran / Reflux 2: hydrogenchloride / methanol; dichloromethane / Reflux View Scheme

暂无反应条件数据

1: NaOH / butan-1-ol / 30 h / Heating 2: conc. HCl / CH2Cl2; methanol / 1 h / Ambient temperature 3: 59 percent / CsOH, p-toluenesulfonyl chloride / dioxane View Scheme