3,4,5,7-四甲氧基黄酮合成路线 （共 46 条）
反应条件
potassium hydroxide in ethanol 24 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 32, # 1 p. 166 - 169
反应条件
1: 86 percent / dimethyl dioxirane / acetone; CH2Cl2 / 0.5 h / 0 - 20 °C 2: 96 percent / K2CO3 / acetone / 1 h / Heating 3: 99 percent / BBr3 / CH2Cl2 / 0.5 h / 0 °C View Scheme
参考文献
Tetrahedron, , vol. 60, # 11 p. 2647 - 2655
反应条件
1: 86 percent / dimethyl dioxirane / acetone; CH2Cl2 / 0.5 h / 0 - 20 °C
2: 96 percent / K2CO3 / acetone / 1 h / Heating
View Scheme
参考文献
Chu, Han-Wei; Wu, Huan-Ting; Lee, Yean-Jang
Tetrahedron, 2004 , vol. 60, # 11 p. 2647 - 2655
反应条件
3,3-dimethyldioxirane in dichloromethane; acetone
T=0 - 20°C; 0.5 h;
参考文献
Chu, Han-Wei; Wu, Huan-Ting; Lee, Yean-Jang
Tetrahedron, 2004 , vol. 60, # 11 p. 2647 - 2655
反应条件
boron tribromide in dichloromethane
T=0 - 20°C;
参考文献
AxoGlia Therapeutics S.A.
Patent: EP2112145 A1, 2009 ;
Location in patent: Page/Page column 16 ;
反应条件
1: 86 percent / dimethyl dioxirane / acetone; CH2Cl2 / 0.5 h / 0 - 20 °C
2: 96 percent / K2CO3 / acetone / 1 h / Heating
3: 99 percent / BBr3 / CH2Cl2 / 0.5 h / 0 °C
4: 89 percent / dimethyl dioxirane / acetone; CH2Cl2 / 0.83 h / 0 - 20 °C
View Scheme
参考文献
Chu, Han-Wei; Wu, Huan-Ting; Lee, Yean-Jang
Tetrahedron, 2004 , vol. 60, # 11 p. 2647 - 2655
