1: T=90°C; 16 h; sealed tube protected from light; 2: With sodium carbonate in water

1: 1-bromo-2,2-dimethoxy-propane With hydrogenchloride in water T=90°C; 0.25 h; 2: With sodium hydrogencarbonate in water T=20°C; 3: 3-amino-2-chloropyrazine in water T=90°C; 2.5 h;