1: With tetrabutylammomium bromide; [Me2N]3P=NP(=NEt)[NMe2]2 in dichloromethane
T=-78°C; Michael addition; 0.0833333 h;
2: With lithium hydroxide in tetrahydrofuran; water
T=20°C; 0.166667 h;
3: With hydrogenchloride in ethanol; water
24 h; Heating; Title compound not separated from byproducts;
参考文献
Lee, Jihye; Lee, Yeon-Im; Kang, Myoung Joo; Lee, Yeon-Ju; Jeong, Byeong-Seon; Lee, Jeong-Hee; Kim, Mi-Jeong; Choi, Ji-Yeon; Ku, Jin-Mo; Park, Hyeung-Geun; Jew, Sang-Sup
Journal of Organic Chemistry, 2005 , vol. 70, # 10 p. 4158 - 4161