1: 4-hydroxybutanol With sodium t-butanolate in N,N-dimethyl-formamide T=0 - 20°C; 1 h; 2: 3-(chloromethyl)pyridine monohydrochloride With sodium t-butanolate in N,N-dimethyl-formamide T=-16 - 0°C; 3: With water in dichloromethane Product distribution / selectivity;

1: 4-hydroxybutanol With potassium tert-butylate in N,N-dimethyl-formamide T=0 - 20°C; 1 h; 2: (pyridin-3-yl)methyl chloride With potassium tert-butylate in N,N-dimethyl-formamide T=-20 - 0°C; 3: With water in dichloromethane Product distribution / selectivity;

1: With potassium tert-butylate in N,N-dimethyl-formamide T=-20 - 20°C; 2: With water in dichloromethane Product distribution / selectivity;

1: 4-hydroxybutanol With potassium tert-butylate in N,N-dimethyl-formamide T=10 - 20°C; 2: 3-chloromethylpyridine benzenesulfonate With potassium tert-butylate in N,N-dimethyl-formamide T=10 - 25°C; Product distribution / selectivity;

1: With potassium tert-butylate in N,N-dimethyl-formamide T=-10 - 0°C; 2: With water in dichloromethane Product distribution / selectivity;