1: 4-hydroxybutanol With potassium tert-butylate in N,N-dimethyl-formamide T=0 - 20°C; 1.5 h; 2: 3-(chloromethyl)pyridine monohydrochloride With potassium tert-butylate in N,N-dimethyl-formamide T=-8 - -3°C; 3: With water Product distribution / selectivity;

1: With potassium tert-butylate in N,N-dimethyl-formamide T=-10 - 0°C; 2: With water in dichloromethane Product distribution / selectivity;