N-bromosuccinmide

1.1: 100 percent / sodium hydroxide / ethanol / cooling 2.1: 96 percent / sodium tungstate dihydrate; sulfuric acid; hydrogen peroxide / aliquat 336 / H2O; toluene / 45 °C 3.1: 92 percent / acetic anhydride / dimethylformamide / 24.5 h / 60 °C 4.1: xylene / 16 h / 130 °C 5.1: 110 g / aq. HCl / xylene; tetrahydrofuran / 2 h / 50 °C 6.1: potassium tert-butoxide / tetrahydrofuran / 1 h / -5 °C 6.2: 97 percent / tetrahydrofuran / 20 h / 22 °C 7.1: 94 percent / L-selectride / tetrahydrofuran / 1.5 h / -60 °C 8.1: 96 percent / diisobutylaluminium hydride / toluene / 1 h / -40 °C 9.1: potassium tert-butoxide / tetrahydrofuran / cooling 9.2: tetrahydrofuran; toluene / -20 - 20 °C 10.1: 5.6 kg / aq. HCl / tetrahydrofuran; toluene; dimethylformamide / 2 h / 45 °C 11.1: 74 percent / sulfamic acid; sodium chlorite / CH2Cl2; H2O / 0.5 h View Scheme

1: 90 percent / NaOEt / ethanol / 2 h / Heating 2: 2M NaOH / methanol; H2O / 3 h / 40 °C 3: 92 percent / p-xylene / 2 h / Heating 4: Aspergillus genus acylase; 0.2 M AcONa; 0.2 M NaOH / H2O / 48 h / 38 °C / pH 8.0 View Scheme

暂无反应条件数据

1: 90 percent / NaOEt / ethanol / 2 h / Heating 2: 2M NaOH / methanol; H2O / 3 h / 40 °C 3: 92 percent / p-xylene / 2 h / Heating 4: Aspergillus genus acylase; 0.2 M AcONa; 0.2 M NaOH / H2O / 48 h / 38 °C / pH 8.0 View Scheme

1.1: n-BuLi / tetrahydrofuran / 0.33 h / -78 °C 1.2: 75 percent / tetrahydrofuran / 3.5 h / -78 °C 2.1: aq. HCl / acetonitrile / 16 h / 20 °C 2.2: 18.7 g / triethylamine / CH2Cl2 / 6 h / 20 °C 3.1: aq. LiOH / tetrahydrofuran / 16 h / 20 °C View Scheme

1.1: 100 percent / sodium hydroxide / ethanol / cooling 2.1: 96 percent / sodium tungstate dihydrate; sulfuric acid; hydrogen peroxide / aliquat 336 / H2O; toluene / 45 °C 3.1: 92 percent / acetic anhydride / dimethylformamide / 24.5 h / 60 °C 4.1: xylene / 16 h / 130 °C 5.1: 110 g / aq. HCl / xylene; tetrahydrofuran / 2 h / 50 °C 6.1: potassium tert-butoxide / tetrahydrofuran / 1 h / -5 °C 6.2: 97 percent / tetrahydrofuran / 20 h / 22 °C View Scheme

1.1: 100 percent / sodium hydroxide / ethanol / cooling 2.1: 96 percent / sodium tungstate dihydrate; sulfuric acid; hydrogen peroxide / aliquat 336 / H2O; toluene / 45 °C 3.1: 92 percent / acetic anhydride / dimethylformamide / 24.5 h / 60 °C 4.1: xylene / 16 h / 130 °C 5.1: 110 g / aq. HCl / xylene; tetrahydrofuran / 2 h / 50 °C 6.1: potassium tert-butoxide / tetrahydrofuran / 1 h / -5 °C 6.2: 97 percent / tetrahydrofuran / 20 h / 22 °C 7.1: 94 percent / L-selectride / tetrahydrofuran / 1.5 h / -60 °C 8.1: 96 percent / diisobutylaluminium hydride / toluene / 1 h / -40 °C View Scheme

1.1: n-BuLi / tetrahydrofuran / 0.33 h / -78 °C 1.2: 75 percent / tetrahydrofuran / 3.5 h / -78 °C 2.1: aq. HCl / acetonitrile / 16 h / 20 °C 2.2: 18.7 g / triethylamine / CH2Cl2 / 6 h / 20 °C View Scheme

hexaammonium heptamolybdate tetrahydrate; dihydrogen peroxide in butan-1-ol 5 h; Heating / reflux;