1-苄基-1H-咪唑-5-甲醛合成路线 （共 17 条）
反应条件
1: propionic acid / H2O; acetonitrile / 2 h / 60 °C 2: acetic acid; aq. H2O2 / 3 h / 20 °C 3: pyridine sulfur trioxide; DMSO; NEt3 / 3 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 11, # 14 p. 3193 - 3204
反应条件
1: 78 percent / LiAlH4 / tetrahydrofuran 2: 82 percent / MnO2 View Scheme
参考文献
Synthesis, , # 3 p. 247 - 248
反应条件
1: 7 percent / Na2CO3 / dimethylformamide / 13 h / 100 °C 2: 63 percent / activated MnO2 / dioxane / 6 h / Heating View Scheme
参考文献
Synthesis, , # 1 p. 47 - 49
反应条件
1: t-BuOK / methanol / 4 h 2: 85 percent / NaIO4, K2S2O2(OH)4 / dioxane; H2O / 24 h / 60 °C View Scheme
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 113, # 6 p. 318 - 328
反应条件
sodium hydride 1.) DMF, RT, 5 min, 2.) DMF, RT, overnight; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 52, # 13 p. 2714 - 2726
反应条件
potassium fluoride on basic alumina T=20°C; 27 h; Product distribution; Further Variations:ReagentsTemperatures;
参考文献
Journal of Heterocyclic Chemistry, , vol. 44, # 6 p. 1445 - 1451
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 0.25 h;
参考文献
Cappon, J. J.; Witters, K. D.; Baart, J.; Verdegem, P. J. E.; Hoek, A. C.; et al.
Recueil des Travaux Chimiques des Pays-Bas, 1994 , vol. 113, # 6 p. 318 - 328
