2,3-二氢-1,4-苯并二噁英-2-羧酰胺盐酸盐合成路线 （共 7 条）
反应条件
in ethanol 1.5 h; Heating;
参考文献
Davrinche; Nguyen-Tri-Xuong; Reynaud; Arnould-Guerin; Tran; Rinjard; Pieri
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 5 p. 397 - 401
反应条件
in ethanol 2 h; Heating;
参考文献
Davrinche; Nguyen-Tri-Xuong; Reynaud; Arnould-Guerin; Tran; Rinjard; Pieri
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 5 p. 397 - 401
反应条件
in ethanol 3.75 h; Heating;
参考文献
Davrinche; Nguyen-Tri-Xuong; Reynaud; Arnould-Guerin; Tran; Rinjard; Pieri
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 5 p. 397 - 401
反应条件
ammonium chloride in ethanol
3.5 h; Heating;
参考文献
Davrinche, C; Nguyen-Tri-Xuong, E; Hamad, Y El; Reynaud, P; Rinjard, P; Tran, G
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 8 p. 765 - 778
反应条件
ammonia in ethanol
T=0 - 10°C; 24 h;
参考文献
Chapleo; Myers; Butler; Doxey; Roach; Smith
Journal of Medicinal Chemistry, 1983 , vol. 26, # 6 p. 823 - 831
反应条件
1: 83 percent / HCl / diethyl ether / 24 h / 0 - 10 °C
2: NH3 / ethanol / 24 h / 0 - 10 °C
View Scheme
参考文献
Chapleo; Myers; Butler; Doxey; Roach; Smith
Journal of Medicinal Chemistry, 1983 , vol. 26, # 6 p. 823 - 831
反应条件
1: 80 percent / carbonate de potassium / acetone / 18 h / Heating
2: 90 percent / methylate de sodium / 24 h / Ambient temperature
3: 97 percent / chlorure d'ammonium / ethanol / 3.5 h / Heating
View Scheme
参考文献
Davrinche; Nguyen-Tri-Xuong; Reynaud; Arnould-Guerin; Tran; Rinjard; Pieri
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 5 p. 397 - 401
