反应条件
1: KOH, pyridine / 0.25 h / 50 °C
2: 65 percent / conc. H2SO4, glacial AcOH / 1 h / Heating
3: 86 percent / BBr3 / CH2Cl2 / Ambient temperature
View Scheme
参考文献
Ares, Jeffrey J.; Outt, Pamela E.; Randall, Jared L.; Murray, Peter D.; Weisshaar, Pamela S.; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 25 p. 4937 - 4943
