850452-53-8合成路线

参考文献

WO2008/8895 A1, ;

Page/Page column 164 ;
WO 2008/008895 A1

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2008/8895 A1, 2008 ;
Location in patent: Page/Page column 163 ;
WO 2008/008895 A1

75-36-5乙酰氯+

109384-19-2N-Boc-4-羟基哌啶

850452-53-8

参考文献

Kikuchi, Tatsuya; Zhang, Ming-Rong; Ikota, Nobuo; Fukushi, Kiyoshi; Okamura, Toshimitsu; Suzuki, Kazutoshi; Arano, Yasushi; Irie, Toshiaki
Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2577 - 2583

24424-99-5二碳酸二叔丁酯

850452-53-8

参考文献

Zhang, Ming-Rong; Furutsuka, Kenji; Maeda, Jun; Kikuchi, Tatsuya; Kida, Takayo; Okauchi, Takashi; Irie, Toshiaki; Suzuki, Kazutoshi
Bioorganic and medicinal chemistry, 2003 , vol. 11, # 12 p. 2519 - 2527

5382-17-24-羟基哌啶盐酸盐

850452-53-8

参考文献

Zhang, Ming-Rong; Furutsuka, Kenji; Maeda, Jun; Kikuchi, Tatsuya; Kida, Takayo; Okauchi, Takashi; Irie, Toshiaki; Suzuki, Kazutoshi
Bioorganic and medicinal chemistry, 2003 , vol. 11, # 12 p. 2519 - 2527

5382-16-14-羟基哌啶

850452-53-8

参考文献

SANOFI; CARRY, Jean-Christophe; CHATREAUX, Fabienne; DEPRETS, Stephanie; DUCLOS, Olivier; LEROY, Vincent; MALLART, Sergio; MELON-MANGUER, Dominique; MENDEZ-PEREZ, Maria; VERGNE, Fabrice
Patent: US2013/261106 A1, 2013 ;

5382-16-14-羟基哌啶+

24424-99-5二碳酸二叔丁酯

850452-53-8

参考文献

SANOFI; CARRY, Jean-Christophe; CHATREAUX, Fabienne; DEPRETS, Stéphanie; DUCLOS, Olivier; LEROY, Vincent; MALLART, Sergio; MELON-MANGUER, Dominique; MENDEZ-PEREZ, Maria; VERGNE, Fabrice
Patent: WO2013/150036 A1, 2013 ;

850452-53-8

73775-92-5

参考文献

Zhang, Ming-Rong; Furutsuka, Kenji; Maeda, Jun; Kikuchi, Tatsuya; Kida, Takayo; Okauchi, Takashi; Irie, Toshiaki; Suzuki, Kazutoshi
Bioorganic and medicinal chemistry, 2003 , vol. 11, # 12 p. 2519 - 2527