2-(4-氯-3-硝基苯甲酰)苯甲酸合成路线 （共 10 条）
反应条件
sulfuric acid; nitric acid in water T=5 - 15°C; 1 h;
参考文献
ANGION BIOMEDICA CORP.
Patent: WO2006/36981 A2, 2006 ;
Location in patent: Page/Page column 83-84 ;
反应条件
hydrogen; sodium carbonate; Pt/Al2O3 in water T=60 - 80°C; P=15001.2 - 30002.4 Torr;
参考文献
Zhandarev; Kazin; Mironov
Russian Journal of Organic Chemistry, 2001 , vol. 37, # 5 p. 673 - 676
反应条件
1: With ammonia in water
T=85°C; 18 - 96 h; Heating / reflux;
2: With hydrogenchloride in water
T=0 - 20°C; pH=2 - 7; Product distribution / selectivity;
参考文献
EXELIXIS, INC.; JOSHI, Anagha, Abhijit
Patent: WO2005/112932 A2, 2005 ;
Location in patent: Page/Page column 65-68; 83-84 ;
WO 2005/112932 A2
反应条件
sodium hydroxide in 1,4-dioxane
参考文献
Aventis Pharmaceuticals Products Inc.
Patent: US6127515 A1, 2000 ;
反应条件
sodium hydroxide
T=180°C;
参考文献
Du Pont de Nemours and Co.
Patent: US2107652 , 1936 ;
反应条件
potassium hydroxide
nachfolgend Reduktion;
参考文献
Agfa
Patent: DE281010 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 12, p. 449
反应条件
darauffolgend Reduzieren;
参考文献
Agfa
Patent: DE281010 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 12, p. 448
反应条件
iodine; chlorine; 1,2-dichloro-benzene
T=170 - 180°C;
参考文献
I.G. Farbenind.
Patent: DE621980 , 1933 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 22, p. 244
反应条件
phosphorus pentoxide; anhydrous trichlorobenzene
T=205°C;
参考文献
I.G. Farbenind.
Patent: DE592366 , 1932 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 20, p. 1296
反应条件
phosphorus pentoxide; anhydrous trichlorobenzene
T=205°C;
参考文献
I.G. Farbenind.
Patent: DE592366 , 1932 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 20, p. 1296
