1-[(4-甲基苯基)磺酰基]-1H-吡咯并[2,3-b]吡啶-5-羧酸甲酯合成路线 （共 2 条）
反应条件
sodium methylate in methanol T=65°C; 1 h;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2005/28475 A2, 2005 ;
Location in patent: Page/Page column 141-142; 222 ;
WO 2005/028475 A2
反应条件
triethylamine; palladium diacetate; triphenylphosphine in DMF (N,N-dimethyl-formamide)
T=100°C; 6 h;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2005/28475 A2, 2005 ;
Location in patent: Page/Page column 140-141; 222 ;
WO 2005/028475 A2
