2-硼-1H-吲哚-1,6-二羧酸-1-(1,1-二甲基乙基)6-甲酯合成路线 （共 3 条）
反应条件
1.1: 4-(N,N-dimethlyamino)pyridine / tetrahydrofuran / 2 h / 20 °C
2.1: lithium diisopropyl amide; tri-isopropoxy-borane / hexane; tetrahydrofuran / 2.5 h / -5 °C
2.2: Cooling with ice
View Scheme
参考文献
JAPAN TOBACCO INC.
Patent: US2011/306599 A1, 2011 ;
反应条件
1.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C
1.2: 2 h / 20 °C
2.1: 4-(N,N-dimethlyamino)pyridine / tetrahydrofuran / 2 h / 20 °C
3.1: lithium diisopropyl amide; tri-isopropoxy-borane / hexane; tetrahydrofuran / 2.5 h / -5 °C
3.2: Cooling with ice
View Scheme
参考文献
JAPAN TOBACCO INC.
Patent: US2011/306599 A1, 2011 ;
反应条件
1.1: 4-(N,N-dimethlyamino)pyridine / tetrahydrofuran / 2 h / 20 °C
2.1: lithium diisopropyl amide; tri-isopropoxy-borane / hexane; tetrahydrofuran / 2.5 h / -5 °C
2.2: Cooling with ice
View Scheme
参考文献
JAPAN TOBACCO INC.
Patent: US2011/306599 A1, 2011 ;
