3-环戊烯-1,1-二甲酸二甲酯合成路线 （共 20 条）
反应条件
Grubb's 2nd generation catalyst in dichloromethane T=20°C; 7 h; Inert atmosphere;
参考文献
Oliveira, Caio C.; Dos Santos, Emerson A. F.; Bormio Nunes, Julia H.; Correia, Carlos Roque D.
Journal of Organic Chemistry, 2012 , vol. 77, # 18 p. 8182 - 8190,9
反应条件
1: With sodium hydride; tetrakis(triphenylphosphine) palladium(0) in dichloromethane T=20°C; 2: With Grubb's 2nd generation catalyst in dichloromethane 4 h; Heating; Further stages.;
参考文献
Kammerer, Claire; Prestat, Guillaume; Gaillard, Thomas; Madec, David; Poli, Giovanni
Organic Letters, 2008 , vol. 10, # 3 p. 405 - 408
反应条件
1: malonic acid dimethyl ester With lithium hydride in N,N-dimethyl-formamide T=0°C; 4 h; 2: (Z)-1,4-Dichloro-2-butene in N,N-dimethyl-formamide T=0 - 20°C;
参考文献
Broggi, Julie; Joubert, Nicolas; Diez-Gonzalez, Silvia; Berteina-Raboin, Sabine; Zevaco, Thomas; Nolan, Steven P.; Agrofoglio, Luigi A.
Tetrahedron, 2009 , vol. 65, # 6 p. 1162 - 1170
反应条件
RuCl2(=C=C=CPh2)(PCy3)2 in dichloromethane T=20°C; Cyclization; Ring-closure metathesis; 20 h;
参考文献
Fuerstner, Alois; Hill, Anthony F.; Liebl, Monika; Wilton-Ely, James D. E. T.
Chemical Communications, 1999 , # 7 p. 601 - 602
反应条件
1: CH(CH2CH=CH2)(CO2Me)2 With sodium hydride in dichloromethane 2: ethylene,methyl acetate With Grubb's 2nd generation catalyst; tetrakis(triphenylphosphine) palladium(0) in dichloromethane 1 h; Heating; Further stages.;
参考文献
Kammerer, Claire; Prestat, Guillaume; Gaillard, Thomas; Madec, David; Poli, Giovanni
Organic Letters, 2008 , vol. 10, # 3 p. 405 - 408
反应条件
acetic acid; tris(acetonitrile)(η5-2,4-cyclopentadien-1-yl)ruthenium(1+) hexafluorophosphate(1-) T=90°C; 24 h; Product distribution; Further Variations:CatalystsTemperaturesReagents;
参考文献
Varela, Jesus A.; Gonzalez-Rodriguez, Carlos; Rubin, Silvia G.; Castedo, Luis; Saa, Carlos
Journal of the American Chemical Society, 2006 , vol. 128, # 30 p. 9576 - 9577
反应条件
lithium hydride in N,N-dimethyl-formamide T=20°C; 64 h;
参考文献
Denonne, Frederic; Celanire, Sylvain; Christophe, Bernard; Defays, Sabine; Delaunoy, Christel; Delporte, Marie-Laure; Detrait, Eric; Durieu, Veronique; Gillard, Michel; Lamberty, Yves; Lorent, Genevieve; Nicolas, Jean-Marie; van Bellinghen, Alain; van Houtvin, Nathalie; Provins, Laurent
ChemMedChem, 2011 , vol. 6, # 9 p. 1559 - 1565
参考文献
Curators of the University of Missouri; 3M Innovative Properties Company
Patent: US6458865 B2, 2002 ;
反应条件
1: 87 percent / NaOMe / methanol / 3 h / 0 - 20 °C 2: 93 percent / Grubbs' catalyst / CH2Cl2 / 72 h / Heating View Scheme
参考文献
Synlett, , # 5 art. no. D36004ST, p. 765 - 768
参考文献
Curators of the University of Missouri; 3M Innovative Properties Company
Patent: US6458865 B2, 2002 ;
