sodium hydroxide

hydrogen; palladium on activated charcoal in tetrahydrofuran; methanol P=12001 Torr;

boron tribromide in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dichloromethane

1: 100 percent / KOEt / diethyl ether / 20 h / Heating 2: 61 percent / iron powder / acetic acid / 3 h / 80 - 90 °C 3: 95 percent / 2 N NaOH / tetrahydrofuran; methanol / 24 h / Ambient temperature 4: 68 percent / 6 N HCl / methanol / 3 h / Heating 5: 75 percent / hydrogen / Pd on carbon (10percent) / methanol; tetrahydrofuran / 12001 Torr View Scheme

1: 68 percent / 6 N HCl / methanol / 3 h / Heating 2: 75 percent / hydrogen / Pd on carbon (10percent) / methanol; tetrahydrofuran / 12001 Torr View Scheme

1: 95 percent / 2 N NaOH / tetrahydrofuran; methanol / 24 h / Ambient temperature 2: 68 percent / 6 N HCl / methanol / 3 h / Heating 3: 75 percent / hydrogen / Pd on carbon (10percent) / methanol; tetrahydrofuran / 12001 Torr View Scheme

1: 61 percent / iron powder / acetic acid / 3 h / 80 - 90 °C 2: 95 percent / 2 N NaOH / tetrahydrofuran; methanol / 24 h / Ambient temperature 3: 68 percent / 6 N HCl / methanol / 3 h / Heating 4: 75 percent / hydrogen / Pd on carbon (10percent) / methanol; tetrahydrofuran / 12001 Torr View Scheme

hydrogenchloride Behandeln des Reaktionsprodukts in H2O und Aethylacetat mit K3<Fe(CN)6> und NaHCO3;