6-甲氧基-5-三氟甲基-1-萘羧酸合成路线 （共 9 条）
反应条件
potassium permanganate
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 3 p. 255 - 256
反应条件
1: 87 percent / I2, HIO3, H2SO4 / acetic acid 2: 93 percent / Cu / pyridine / 20 h / 120 °C 3: hydrolysis View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 3 p. 255 - 256
反应条件
1: 93 percent / Cu / pyridine / 20 h / 120 °C 2: hydrolysis View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 3 p. 255 - 256
反应条件
potassium permanganate
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 3 p. 255 - 256
反应条件
1: Sommelet reaction 2: KMnO4 View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 3 p. 255 - 256
参考文献
Journal of Pharmaceutical Sciences, , vol. 79, # 7 p. 628 - 633
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 3 p. 255 - 256
参考文献
Journal of Pharmaceutical Sciences, , vol. 79, # 7 p. 628 - 633
反应条件
1: thionyl chloride, DMF / 4 h / Heating
2: sodium azide / acetone; H2O / 0.5 h / 0 °C
3: 2.) 40percent aq. KOH / 1.) toluene, reflux, 1 h, 2.) toluene, reflux, 1 h
View Scheme
参考文献
Malamas, MS; Sestanj, K; Millen, J
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 4 p. 369 - 374
