反应条件
1: phosphorus oxychloride / 0.5 h / 60 °C
2: 43 percent / sodium / Ambient temperature
3: NaOH / methanol; H2O / 1 h / 65 °C
4: 1.) triethylamine, ethylchloroformate / 1.) DMF, 0 deg C, 30 min, 2.) room temp. overnight
View Scheme
参考文献
Dostert; Imbert; Ancher; et al.
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444
