N-BOC-2-甲基-L-丝氨酸合成路线 （共 9 条）
反应条件
sodium hydroxide; triethylamine in methanol T=20°C;
参考文献
Yu, Weiping; McConathy, Jonathan; Olson, Jeffrey; Camp, Vernon M.; Goodman, Mark M.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 26 p. 6718 - 6721
反应条件
sodium tetrahydroborate in tetrahydrofuran; ethanol T=50°C;
参考文献
Fukuyama; Xu
Journal of the American Chemical Society, 1993 , vol. 115, # 18 p. 8449 - 8450
反应条件
lithium hydroxide in tetrahydrofuran; methanol; water T=0°C; 1 h;
参考文献
Angewandte Chemie - International Edition, , vol. 44, # 1 p. 135 - 138
反应条件
1: 97 percent / NaOMe / methanol / Heating 2: aq. phosphate buffer pH 7.5 / 23 °C / pig liver esterase 3: 90 percent / NaBH4 / tetrahydrofuran; ethanol / 50 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 115, # 18 p. 8449 - 8450
反应条件
1: aq. phosphate buffer pH 7.5 / 23 °C / pig liver esterase 2: 90 percent / NaBH4 / tetrahydrofuran; ethanol / 50 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 115, # 18 p. 8449 - 8450
反应条件
1: 94 percent / H2 / Pd/C / ethyl acetate / 20 °C 2: NaIO4; aq. NaHCO3 / CH2Cl2 3: NaClO2; NaH2PO4; 2-methyl-2-butene / 2-methyl-propan-2-ol View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 33 p. 5847 - 5849
反应条件
1: NaIO4; aq. NaHCO3 / CH2Cl2 2: NaClO2; NaH2PO4; 2-methyl-2-butene / 2-methyl-propan-2-ol View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 33 p. 5847 - 5849
反应条件
in methanol; hexane; benzene
T=20°C; 0.5 h;
参考文献
Yu, Weiping; McConathy, Jonathan; Olson, Jeffrey; Camp, Vernon M.; Goodman, Mark M.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 26 p. 6718 - 6721
反应条件
in diethyl ether
T=0°C; 0.5 h; Yield given;
参考文献
Chakraborty, Tushar Kanti; Sudhakar, Gangarajula
Tetrahedron Letters, 2006 , vol. 47, # 33 p. 5847 - 5849
