2-(4-甲氧基苯基)-5-苯基-1,3,4-恶二唑合成路线 （共 37 条）
反应条件
1: N-methylimidazole / CH2Cl2 / 0.5 h / 0 - 20 °C
View Scheme
参考文献
Cesarini, Sara; Colombo, Nicoletta; Pulici, Maurizio; Felder, Eduard R.; Brill, Wolfgang K.-D.
Tetrahedron, 2006 , vol. 62, # 43 p. 10223 - 10236
反应条件
Nafion(R)NR50
T=80°C; 0.166667 h; microwave irradiation;
参考文献
Polshettiwar, Vivek; Varma, Rajender S.
Tetrahedron Letters, 2008 , vol. 49, # 5 p. 879 - 883
反应条件
1.1: sodium carbonate / dioxane / 40 °C
1.2: 81 percent / dioxane / 24 h / 20 °C
2.1: 87 percent / phosphorous oxychloride / 24 h / 80 °C
View Scheme
参考文献
Lee; Chen; Wei; Fann
Journal of the American Chemical Society, 2001 , vol. 123, # 10 p. 2296 - 2307
反应条件
[2,2']bipyridinyl; CuF2; [(diglyme)NiBr2]; cesium fluoride in N,N-dimethyl acetamide
T=150°C; Inert atmosphere;
参考文献
Hachiya, Hitoshi; Hirano, Koji; Satoh, Tetsuya; Miura, Masahiro
Angewandte Chemie - International Edition, 2010 , vol. 49, # 12 p. 2202 - 2205
反应条件
T=110°C; 0.25 h; Microwave irradiation;
参考文献
Efimova; Artamonova; Koldobskii
Russian Journal of Organic Chemistry, 2008 , vol. 44, # 9 p. 1345 - 1347
反应条件
1.1: NaHCO3; AcONa / H2O
1.2: 73 percent / H2SO4 / 2 h / 20 °C
2.1: 96 percent / iPentONO2; CuBr2 / acetonitrile / 2 h / 20 °C
3.1: 85 percent / aq. Na2CO3 / Pd(PPh3)4 / dimethylformamide / 3 h / 85 °C
View Scheme
参考文献
Vachal, Petr; Toth, Leslie M.
Tetrahedron Letters, 2004 , vol. 45, # 38 p. 7157 - 7161
反应条件
1: 96 percent / iPentONO2; CuBr2 / acetonitrile / 2 h / 20 °C
2: 85 percent / aq. Na2CO3 / Pd(PPh3)4 / dimethylformamide / 3 h / 85 °C
View Scheme
参考文献
Vachal, Petr; Toth, Leslie M.
Tetrahedron Letters, 2004 , vol. 45, # 38 p. 7157 - 7161
反应条件
1: hexamethylphosphoric acid triamide / 1 h / 20 °C
2: hexamethylphosphoric acid triamide / 0.01 h / microwave irradiation
View Scheme
参考文献
Mashraqui, Sabir H.; Ghadigaonkar, Shailesh G.; Kenny, Rajesh S.
Synthetic Communications, 2003 , vol. 33, # 14 p. 2541 - 2545
反应条件
1: 95 percent / ethanol / 5 h / Heating
2: 82 percent / aq. cerium ammonium nitrate / acetonitrile / 25 °C
View Scheme
参考文献
Said, S. B.; Elagamey, A. A.; Khadr, R. E.
Egyptian Journal of Chemistry, 2003 , vol. 46, # 6 p. 881 - 888
反应条件
in ethanol
0.25 h; Heating;
参考文献
Paetzel, Michael; Liebscher, Juergen
Journal fuer Praktische Chemie (Leipzig), 1991 , vol. 333, # 1 p. 149 - 151
