2-氯-4-氟苯甲醛合成路线

参考文献

FMC Corporation
Patent: US4846882 A1, 1989 ;

参考文献

Musso, David L.; Orr, G. Faye; Cochran, Felicia R.; Kelley, James L.; Selph, Jeffrey L.; Rigdon, Greg C.; Cooper, Barrett R.; Jones, Michael L.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 3 p. 409 - 416

84194-36-52-氯-4-氟苯甲醛

1260666-80-55-氟异吲哚啉-1-酮

参考文献

GILEAD CONNECTICUT, INC.; GENENTECH, INC.; CURRIE, Kevin S.; WANG, Xiaojing; YOUNG, Wendy, B.
Patent: WO2012/30990 A1, 2012 ;
WO 2012/030990 A1

84194-36-52-氯-4-氟苯甲醛

174603-38-43-(2-氯-4-氟苯基)-丙酸

参考文献

Musso, David L.; Orr, G. Faye; Cochran, Felicia R.; Kelley, James L.; Selph, Jeffrey L.; Rigdon, Greg C.; Cooper, Barrett R.; Jones, Michael L.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 3 p. 409 - 416

84194-36-52-氯-4-氟苯甲醛

118630-33-41-(2-氯-4-氟苄基)哌嗪

参考文献

Meyer; Tomcufcik; Chan; Haug
Journal of Medicinal Chemistry, 1989 , vol. 32, # 3 p. 593 - 597

84194-36-52-氯-4-氟苯甲醛+

100-51-6苯甲醇

117490-57-04-(苄氧基)-2-氯苯甲醛

参考文献

Cho, Hoon; Wu, Ying; Choi, Cheol-Hee
Patent: US2011/269954 A1, 2011 ;
Location in patent: Page/Page column 30-31 ;
US 20110269954 A1

110-89-4哌啶+

84194-36-52-氯-4-氟苯甲醛

886501-12-82-氯-4-(1-哌啶基)苯甲醛

参考文献

Yongpruksa, Nattawut; Pandey, Siddharth; Baker, Gary A.; Harmata, Michael
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 23 p. 7979 - 7982

110-91-8吗啉+

84194-36-52-氯-4-氟苯甲醛

886501-36-62-氯-4-(4-吗啉基)苯甲醛

参考文献

Yongpruksa, Nattawut; Pandey, Siddharth; Baker, Gary A.; Harmata, Michael
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 23 p. 7979 - 7982

123-75-1四氢吡咯+

84194-36-52-氯-4-氟苯甲醛

886500-65-82-氯-4-(1-吡咯烷基)苯甲醛

参考文献

Yongpruksa, Nattawut; Pandey, Siddharth; Baker, Gary A.; Harmata, Michael
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 23 p. 7979 - 7982

84194-36-52-氯-4-氟苯甲醛

99329-85-82-氯-4-氟-5-硝基苯甲醛

参考文献

GLAXO GROUP LIMITED
Patent: WO2007/36718 A2, 2007 ;
Location in patent: Page/Page column 87 ;
WO 2007/036718 A2