2-(2,5-二甲基-1H-吡咯-1-基)-苯羧酸甲酯合成路线 (共 6 条)
反应条件
acetic acid T=100°C; Paal-Knorr Pyrrole Synthesis; Inert atmosphere;
参考文献
WO2014/71247 A1, ;
Paragraph 00314 ;
反应条件
diazomethane; diethyl ether
参考文献
Journal of Organic Chemistry, , vol. 20, p. 225,228
反应条件
1: ethanol; acetic acid 2: diazomethane; diethyl ether View Scheme
参考文献
Journal of Organic Chemistry, , vol. 20, p. 225,228
反应条件
1: ethanol; acetic acid 2: diazomethane; diethyl ether View Scheme
参考文献
Journal of Organic Chemistry, , vol. 20, p. 225,228
反应条件
water; lithium hydroxide hydrate in tetrahydrofuran; methanol T=20°C;
参考文献
DANA-FARBER CANCER INSTITUTE, INC.; WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH; BRADNER, James, E.; MCKEOWN, Michael, R.; RAHL, Peter, B.; YOUNG, Richard, A.; MARINEAU, Jason, J.
Patent: WO2014/71247 A1, 2014 ;
Location in patent: Paragraph 00315 ;
参考文献
Shirley et al.
Journal of Organic Chemistry, 1955 , vol. 20, p. 225,228