1-(2,4-二硝基苯基)哌啶合成路线 （共 93 条）
反应条件
1: ethanol; water / 25 °C / pH 8.48
2: triethylamine / N,N-dimethyl-formamide / 80 °C / |Inert atmosphere
3: ethanol; water / 25 °C / pH 11.12
View Scheme
参考文献
Aguayo, Raul; Arias, Felipe; Canete, Alvaro; Zuniga, Carolina; Castro, Enrique A.; Pavez, Paulina; Santos, Jose G.
International Journal of Chemical Kinetics, 2013 , vol. 45, # 3 p. 202 - 211
反应条件
triethylamine in benzene
T=25°C; other solv., and var. oxygen and nitrogen-containing bases; Rate constantMechanism;
参考文献
Vizgert, R. V.; Sheiko, S. G.; Kulishova, T. P.; Sukharevskaya, L. E.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 6.1 p. 1048 - 1052
Zhurnal Organicheskoi Khimii, 1989 , vol. 25, # 6 p. 1164 - 1169
反应条件
in 1,4-dioxane; water
T=30°C; ionic strength O.1M (NaCl); reaction with piperidine in the presence and absence of NaOH, NaOH concentration dependence; aminodephenoxylation with pyrrolidine and piperidine and hydroxydephenylation with NaOH of substituted diphenyl ethers; Rate constantMechanism;
参考文献
Bunnett, Joseph F.; Cartano, Artemio V.
Journal of the American Chemical Society, 1981 , vol. 103, # 16 p. 4861 - 4865
反应条件
/BRN= 102438/ in benzene
T=100°C; Rate constant;
参考文献
Pietra,F. et al.
Journal of the Chemical Society [Section] B: Physical Organic, 1968 , p. 1595 - 1600
反应条件
piperidine in dimethyl sulfoxide
T=25 - 48.2°C; Kinetics;
参考文献
Pietra,F. et al.
Journal of the Chemical Society [Section] B: Physical Organic, 1970 , p. 1659 - 1667
反应条件
hydroxide in water
T=25°C; various concentrations, various pH; Rate constantMechanism;
参考文献
Vargas, Elba B. de; Rossi, Rita H. de
Journal of Organic Chemistry, 1984 , vol. 49, # 21 p. 3978 - 3983
反应条件
T=0°C; Rate constant;
参考文献
Bunnett et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 385,390
参考文献
Le Fevre
Journal of the Chemical Society, 1932 , p. 1376,1378
参考文献
Le Fevre
Journal of the Chemical Society, 1930 , p. 147,149
反应条件
water in acetonitrile
T=35°C; var. conc. of reagents; Rate constant;
参考文献
Bhattacharjee, Gurudas; Singh, Ashok Kumar; Saikia, Ranjumoni; Yadav, Sudha
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 12 p. 1214 - 1217
