5-氟-2,3-二氢-6-甲氧基-1H-茚-1-酮合成路线 (共 6 条)
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1199304 A1, 2002 ;
Location in patent: Referential example 9 ;
EP 1199304 A1
反应条件
aluminium trichloride in carbon disulfide T=0 - 10°C; 1 h;
参考文献
Kikumoto; Tobe; Fukami; Egawa
Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 246 - 250
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5922771 A1, 1999 ;
参考文献
US5780470 A1, ;
US 5780470 A
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5922771 A1, 1999 ;
反应条件
boron tribromide in dichloromethane
T=20°C; 7 h; Cooling with ice;
参考文献
DAINIPPON SUMITOMO PHARMA CO., LTD.
Patent: US2012/225876 A1, 2012 ;
Location in patent: Page/Page column 58-59 ;