(S)-3-氨基-3-苯基丙酸盐酸盐合成路线 （共 21 条）
反应条件
hydrogenchloride in water T=100°C; 2 h;
参考文献
Zhu, Hao; Jiang, Xianxing; Li, Xinghua; Hou, Chen; Jiang, Yu; Hou, Ke; Wang, Rui; Li, Yanfeng
ChemCatChem, 2013 , vol. 5, # 8 p. 2187 - 2190
反应条件
hydrogenchloride in diethyl ether 18 h; Ambient temperature;
参考文献
Laschat, Sabine; Kunz, Horst
Journal of Organic Chemistry, 1991 , vol. 56, # 20 p. 5883 - 5889
反应条件
hydrogenchloride in diethyl ether T=20°C; 0.5 h;
参考文献
Ramachandran, P. Veeraraghavan; Burghardt, Thomas E.
Chemistry - A European Journal, 2005 , vol. 11, # 15 p. 4387 - 4395
反应条件
hydrogenchloride 2 h; Heating;
参考文献
Forro, Eniko; Paal, Tihamer; Tasnadi, Gabor; Fueloep, Ferenc
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 7-8 p. 917 - 923
反应条件
hydrogenchloride; sodium hydroxide 16 h; Ambient temperature;
参考文献
Wasserman, Harry H.; Berger, Gregory D.
Tetrahedron, 1983 , vol. 39, # 15 p. 2459 - 2464
反应条件
hydrogenchloride in 1,4-dioxane T=20°C; 0.5 h;
参考文献
Science China Chemistry, , vol. 54, # 1 p. 61 - 65
反应条件
1: aq. NaClO2; NaH2PO4; 2-methyl-2-butene / 2-methyl-propan-2-ol / 1 h / 20 °C 2: 0.49 g / HCl / diethyl ether / 0.5 h / 20 °C View Scheme
参考文献
Chemistry - A European Journal, , vol. 11, # 15 p. 4387 - 4395
反应条件
1.1: diethyl ether / 6 h / 20 °C 2.1: O3 / CH2Cl2; methanol / 1 h / -78 °C 2.2: Me2S / CH2Cl2; methanol / 1 h / -78 - 20 °C 3.1: aq. NaClO2; NaH2PO4; 2-methyl-2-butene / 2-methyl-propan-2-ol / 1 h / 20 °C 4.1: 0.49 g / HCl / diethyl ether / 0.5 h / 20 °C View Scheme
参考文献
Chemistry - A European Journal, , vol. 11, # 15 p. 4387 - 4395
反应条件
1.1: O3 / CH2Cl2; methanol / 1 h / -78 °C 1.2: Me2S / CH2Cl2; methanol / 1 h / -78 - 20 °C 2.1: aq. NaClO2; NaH2PO4; 2-methyl-2-butene / 2-methyl-propan-2-ol / 1 h / 20 °C 3.1: 0.49 g / HCl / diethyl ether / 0.5 h / 20 °C View Scheme
参考文献
Chemistry - A European Journal, , vol. 11, # 15 p. 4387 - 4395
反应条件
1: 82 percent / 2 M aq. NaOH / 1 h / 0 °C 2: N-methylmorpholine / 0.5 h / -5 °C 3: 51 percent / diethyl ether; tetrahydrofuran 4: 91 percent / Et3N, silver benzoate / 3 h 5: 77 percent / H2, conc. HCl / 10percent Pd/C / methanol / 3.5 h / 760 Torr / Ambient temperature 6: 74 percent / 10percent aq. NaOH / 3 h View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 17 p. 2047 - 2054
