1: KOH / ethanol / 20 °C 2: 93 percent / (NMe4)Co(III)Me2opba*2H2O*CH3CN; pivalaldehyde; O2 / acetonitrile / 3 h View Scheme

pyridine; trifluoromethylsulfonic anhydride in dichloromethane T=0 - 20°C;

1: 92 percent / pyridine, 4-(dimethylamino)pyridine / CH2Cl2 / 48 h / 20 °C 2: 1.) sodium α-(dimethylamino)naphthalenide / 1.) benzene, HMPA, 30 s, 2.) 30 min 3: 89 percent / KOH/H2O / ethane-1,2-diol / 2 h / Heating View Scheme