反应条件
1: 1.) LDA / 1.) THF, -78 deg C, 1 h; 2.) -78 deg C to RT 2: 1.) zinc acetate; 2.) 5 percent KOH / 1.) acetic acid, reflux, 1 h; 2.) MeOH, reflux, 0.5 h 3: N,N-diethylcyclohexylamine / dioxane / 2 h / 60 °C 4: LiAlH4 / diethyl ether / 1 h / 0 °C 6: (n-Bu)3SnH / toluene / 3 h / Heating 7: 2 N HCl / tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 34, # 5 p. 2061 - 2065
