(S)-3-二甲基氨基-3-苯丙醇合成路线 （共 13 条）
反应条件
1: With sodium tetrahydroborate in tetrahydrofuran 2: With methanesulfonic acid in tetrahydrofuran T=30°C; 3: With sodium hydroxide in tetrahydrofuran; water pH=9 - 10;
参考文献
WO2011/161690 A1, ;
Page/Page column 25 ;
反应条件
formic acid in water 8 h; Heating;
参考文献
Tetrahedron Asymmetry, , vol. 18, # 17 p. 2099 - 2103
反应条件
caustic lye in dichloromethane; water T=20°C; 0.166667 h;
参考文献
WO2011/161690 A1, ;
Page/Page column 27 ;
反应条件
lithium aluminium tetrahydride; aluminium trichloride in diethyl ether T=0°C;
参考文献
Journal of Organic Chemistry, , vol. 47, # 20 p. 4004 - 4005
反应条件
1: With sodium tetrahydroborate in tetrahydrofuran 2: With methanesulfonic acid in tetrahydrofuran T=30°C; 3: With sodium hydroxide in tetrahydrofuran; water pH=9 - 10; Product distribution / selectivity;
参考文献
WO2011/161690 A1, ;
Page/Page column 26 ;
反应条件
nickel in ethanol Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 47, # 20 p. 4004 - 4005
反应条件
formic acid in water 12 h; Reflux;
参考文献
Advanced Synthesis and Catalysis, , vol. 352, # 2-3 p. 395 - 406
反应条件
1: benzene / 20 h / Heating 2: 72 percent 3: 94 percent / TiCl3, AcOH, AcONa / Ambient temperature 4: Raney Ni / ethanol / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 47, # 20 p. 4004 - 4005
反应条件
1: 94 percent / TiCl3, AcOH, AcONa / Ambient temperature 2: Raney Ni / ethanol / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 47, # 20 p. 4004 - 4005
反应条件
1: 72 percent 2: 94 percent / TiCl3, AcOH, AcONa / Ambient temperature 3: Raney Ni / ethanol / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 47, # 20 p. 4004 - 4005
