n-(4-氨基苯基)氨基甲酸苄酯合成路线 （共 8 条）
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane
T=0 - 20°C;
参考文献
Hasserodt, Jens; Janda, Kim D.
Tetrahedron, 1997 , vol. 53, # 33 p. 11237 - 11256
反应条件
Fe3O4Rh; hydrazine hydrate in ethanol
T=80°C; 5 h; Inert atmosphere;
参考文献
Jang, Youngjin; Kim, Seyoung; Jun, Samuel Woojoo; Kim, Byung Hyo; Hwang, Sunhwan; Song, In Kyu; Kim, B. Moon; Hyeon, Taeghwan
Chemical Communications, 2011 , vol. 47, # 12 p. 3601 - 3603
反应条件
in 2,2,2-trifluoroethanol
T=150°C; 2 h; microwave irradiation;
参考文献
F. Hoffmann-La Roche AG
Patent: EP2070899 A1, 2009 ;
Location in patent: Page/Page column 5-6 ;
反应条件
sodium dithionite in 1,4-dioxane; water
Reduction; 0.5 h; Heating;
参考文献
Velikorodov
Russian Journal of Organic Chemistry, 2000 , vol. 36, # 2 p. 233 - 239
反应条件
1: acetone / Ambient temperature
2: aq. acid
View Scheme
参考文献
Rewcastle; Baguley; Cain
Journal of Medicinal Chemistry, 1982 , vol. 25, # 10 p. 1231 - 1235
反应条件
1: 87 percent / MgO / acetone / 12 h / Ambient temperature
2: 92 percent / Fe, conc. aq. HCl / dimethylformamide; H2O / 0.5 h / Heating
View Scheme
参考文献
Rewcastle; Baguley; Cain
Journal of Medicinal Chemistry, 1982 , vol. 25, # 10 p. 1231 - 1235
反应条件
1: acetone / Ambient temperature
2: aq. acid
View Scheme
参考文献
Rewcastle; Baguley; Cain
Journal of Medicinal Chemistry, 1982 , vol. 25, # 10 p. 1231 - 1235
反应条件
1: 73 percent / HSO3ONO / acetic acid / 0.5 h / 0 °C
2: 87 percent / Na2S2O4 / dioxane; H2O / 0.5 h / Heating
View Scheme
参考文献
Velikorodov
Russian Journal of Organic Chemistry, 2000 , vol. 36, # 2 p. 233 - 239
