alpha,alpha-二甲基苯乙酸合成路线 （共 89 条）
反应条件
potassium carbonate in dimethyl sulfoxide T=90°C; 16 h; Inert atmosphereGreen chemistry;
参考文献
Ji, Yuan; Sweeney, Jessica; Zoglio, Jillian; Gorin, David J.
Journal of Organic Chemistry, 2013 , vol. 78, # 22 p. 11606 - 11611
反应条件
methanol in hexane; benzene T=20°C; 0.166667 h;
参考文献
Noji, Masahiro; Sunahara, Haruka; Tsuchiya, Ken-Ichi; Mukai, Toru; Komasaka, Ayako; Ishii, Keitaro
Synthesis, 2008 , # 23 art. no. F16908SS, p. 3835 - 3845
反应条件
1: SOCl2 / 1 h 2: 1 h / Heating View Scheme
参考文献
Morton; Eisenmann
Journal of Organic Chemistry, 1958 , vol. 23, p. 1469,1472
参考文献
Dyllick-Brenzinger, Rainer A.; Patel, Vijay; Rampersad, Mollin B.; Stothers, J. B.; Thomas, Shirley E.
Canadian Journal of Chemistry, 1990 , vol. 68, # 7 p. 1106 - 1115
反应条件
1: thionyl chloride / |Reflux 2: nitric acid; sulfuric acid / 20 °C 3: iron; ammonium chloride / ethanol; water / |Reflux View Scheme
参考文献
Li, Yanyang; Shi, Xiangfei; Xie, Ning; Zhao, Yanjin; Li, Shuxin
MedChemComm, 2013 , vol. 4, # 2 p. 367 - 370
反应条件
bromine; mercury(II) oxide in tribromo methane T=8°C; 0.25 h;
参考文献
Sychkova, L. D.; Shabarov, Yu. S.
Journal of Organic Chemistry USSR (English Translation), 1980 , vol. 16, # 10 p. 1775 - 1779
Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 10 p. 2086 - 2091
反应条件
sodium acetate; palladium diacetate; silver carbonate in 1,4-dioxane T=150°C; P=760.051 Torr; 18 h;
参考文献
Giri, Ramesh; Yu, Jin-Quan
Journal of the American Chemical Society, 2008 , vol. 130, # 43 p. 14082 - 14083
反应条件
1: CCl4; iron; bromine 2: LiAlH4; diethyl ether View Scheme
参考文献
Heck; Winstein
Journal of the American Chemical Society, 1957 , vol. 79, p. 3432,3437
反应条件
thionyl chloride; benzene
参考文献
Zajaczkowska-Terpinska,E.; Bisanz,T.
Roczniki Chemii, 1975 , vol. 49, p. 2017 - 2024
参考文献
Varian Medical Systems,Inc.
Patent: US2009/304589 A1, 2009 ;
