5-溴-2-甲氧基-苯丙酸合成路线 （共 7 条）
反应条件
aluminium trichloride; nitrobenzene
参考文献
Barnes; Kraft; Gordon
Journal of the American Chemical Society, 1949 , vol. 71, p. 3523,3527
反应条件
potassium hydroxide in methanol
RefluxInert atmosphere;
参考文献
Williams, John D.; Khan, Atiyya R.; Cardinale, Steven C.; Butler, Michelle M.; Bowlin, Terry L.; Peet, Norton P.
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 419 - 434
反应条件
tetrachloromethane; bromine
T=-10°C;
参考文献
Barnes; Kraft; Gordon
Journal of the American Chemical Society, 1949 , vol. 71, p. 3523,3527
反应条件
ethanol
T=180°C; Erhitzen des Reaktionsprodukts mit wss.-methanol. Kalilauge;
参考文献
Barnes; Kraft; Gordon
Journal of the American Chemical Society, 1949 , vol. 71, p. 3523,3527
反应条件
1: potassium tert-butylate / tetrahydrofuran / 0 - 20 °C / |Inert atmosphere
2: hydrogen; 5 Rh/alumina / methanol / 6 h / 760.05 Torr
3: potassium hydroxide / methanol / |Reflux; |Inert atmosphere
View Scheme
参考文献
Williams, John D.; Khan, Atiyya R.; Cardinale, Steven C.; Butler, Michelle M.; Bowlin, Terry L.; Peet, Norton P.
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 419 - 434
反应条件
1: hydrogen; 5 Rh/alumina / methanol / 6 h / 760.05 Torr
2: potassium hydroxide / methanol / |Reflux; |Inert atmosphere
View Scheme
参考文献
Williams, John D.; Khan, Atiyya R.; Cardinale, Steven C.; Butler, Michelle M.; Bowlin, Terry L.; Peet, Norton P.
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 419 - 434
反应条件
T=180°C; und Erhitzen des Reaktionsgemisches mit Wasser;
参考文献
Barnes; Kraft; Gordon
Journal of the American Chemical Society, 1949 , vol. 71, p. 3523,3527
