2-氨基-3-氟苯甲酸合成路线

825-22-92-氨基-3-氟苯甲酸→132715-69-62-溴-3-氟苯甲酸

参考文献

Kawahara, Eiji; Miyake, Takahiro; Roesel, Johannes
Patent: US2008/293708 A1, 2008 ;
Location in patent: Page/Page column 37 ;

825-22-92-氨基-3-氟苯甲酸→111721-75-62-溴-3-氟苯胺

参考文献

McKittrick, Brian; Failli, Amedeo; Steffan, Robert J.; Soll, Richard M.; Hughes, Philip; et al.
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 7 p. 2151 - 2163

67-56-1甲醇+825-22-92-氨基-3-氟苯甲酸→144851-82-12-氨基-3-氟苯甲酸甲酯

参考文献

Siegel, Dustin; Sperandio, David; Yang, Hai; Sangi, Michael; Parrish, Jay P.; Hui, Hon Chung
Patent: US2013/273037 A1, 2013 ;
Location in patent: Paragraph 0808-0811 ;

825-22-92-氨基-3-氟苯甲酸→132715-70-9

参考文献

McKittrick, Brian; Failli, Amedeo; Steffan, Robert J.; Soll, Richard M.; Hughes, Philip; et al.
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 7 p. 2151 - 2163

825-22-92-氨基-3-氟苯甲酸→854538-94-62-氨基-3-氟苯甲醛

参考文献

Ida, Yoshihiro; Matsubara, Ayaka; Nemoto, Toru; Saito, Manabu; Hirayama, Shigeto; Fujii, Hideaki; Nagase, Hiroshi
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 19 p. 5810 - 5831

825-22-92-氨基-3-氟苯甲酸→874784-14-22-氨基-5-溴-3-氟苯甲酸

参考文献

BLUEPRINT MEDICINES; BIFULCO, Neil, Jr.; BROOIJMANS, Natasja; HODOUS, Brian, L.; KIM, Joseph, L.; MIDUTURU, Chandrasekhar, V.
Patent: WO2014/11900 A2, 2014 ;
Location in patent: Page/Page column 77 ;

825-22-92-氨基-3-氟苯甲酸→906811-49-2(2-氨基-3-氟苯基)甲醇

参考文献

Ida, Yoshihiro; Matsubara, Ayaka; Nemoto, Toru; Saito, Manabu; Hirayama, Shigeto; Fujii, Hideaki; Nagase, Hiroshi
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 19 p. 5810 - 5831

825-22-92-氨基-3-氟苯甲酸→953039-25-36-溴-2-氯-8-氟喹唑啉

参考文献

BLUEPRINT MEDICINES; BIFULCO, Neil, Jr.; BROOIJMANS, Natasja; HODOUS, Brian, L.; KIM, Joseph, L.; MIDUTURU, Chandrasekhar, V.
Patent: WO2014/11900 A2, 2014 ;