1-(三异丙基硅基)-1-丙炔合成路线 （共 14 条）
反应条件
1.1: n-BuLi / hexane; tetrahydrofuran / 2.5 h / -78 °C 1.2: 91 percent / tetrahydrofuran; hexane / -78 - 20 °C 2.1: n-BuLi / hexane; tetrahydrofuran / 0.25 h / -78 °C 2.2: 98 percent / I2 / tetrahydrofuran; hexane / -78 - 20 °C View Scheme
参考文献
Teply, Filip; Stara, Irena G.; Stary, Ivo; Kollarovic, Adrian; Saman, David; Vyskocil, Stepan; Fiedler, Pavel
Journal of Organic Chemistry, 2003 , vol. 68, # 13 p. 5193 - 5197
反应条件
1: tris(1-methylethyl)(prop-1-yn-1-yl)silane With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 2.5 h; 2: 1-bromonaphthalen-2-ylmethyl bromide in tetrahydrofuran; hexane T=-78 - 20°C;
参考文献
Teply, Filip; Stara, Irena G.; Stary, Ivo; Kollarovic, Adrian; Saman, David; Vyskocil, Stepan; Fiedler, Pavel
Journal of Organic Chemistry, 2003 , vol. 68, # 13 p. 5193 - 5197
反应条件
n-butyllithium; 1,4-diaminobutane in diethyl ether
T=-15°C; 2 h;
参考文献
Corey, E. J.; Ruecker, Cristoph
Tetrahedron Letters, 1982 , vol. 23, # 7 p. 719 - 722
反应条件
1: n-butyllithium-tetramethylene diamine / diethyl ether / 2 h / -15 °C
2: 100 percent / 1 h / -78 - -40 °C
View Scheme
参考文献
Corey, E. J.; Ruecker, Cristoph
Tetrahedron Letters, 1982 , vol. 23, # 7 p. 719 - 722
