N-叔丁氧羰基-L-亮氨醇合成路线 （共 35 条）
反应条件
in dichloromethane Acylation;
参考文献
Christoffers, Jens; Mann, Alexander
Angewandte Chemie - International Edition, 2000 , vol. 39, # 15 p. 2752 - 2754
反应条件
sodium tetrahydroborate; lithium chloride in tetrahydrofuran T=20°C; Inert atmosphere;
参考文献
Spaeth, Andreas; Gonschor, Janina; Koenig, Burkhard
Monatshefte fur Chemie, 2011 , vol. 142, # 12 p. 1289 - 1308
反应条件
hydrogen; palladium on activated charcoal in ethylene glycol dimethyl ether T=20°C; Reduction; P=3800 Torr; 3 h;
参考文献
Falorni, Massimo; Giacomelli, Giampaolo; Porcheddu, Andrea; Taddei, Maurizio
Journal of Organic Chemistry, 1999 , vol. 64, # 24 p. 8962 - 8964
反应条件
borane-THF in tetrahydrofuran 1.) 0 deg C, 1 h; 2.) RT; 3.) 0 deg C, 1 h;
参考文献
Donner
Tetrahedron Letters, 1995 , vol. 36, # 8 p. 1223 - 1226
参考文献
Agouron Pharmaceuticals, Inc.
Patent: US6020371 A1, 2000 ;
反应条件
sodium tetrahydroborate; iodine in tetrahydrofuran T=20°C; Reduction;
参考文献
Naqvi; Bhattacharya; Haq
Journal of Chemical Research - Part S, 1999 , # 7 p. 424 - 425
反应条件
in tetrahydrofuran T=0 - 20°C; 1.5 h;
参考文献
EP1498411 A1, ;
Page/Page column 93 ;
参考文献
Osaka City University; HIROTSUNE, Shinji
Patent: EP2647386 A1, 2013 ;
Location in patent: Page/Page column ;
反应条件
sodium tetrahydroborate in tetrahydrofuran; methanol T=-20°C; 1 h;
参考文献
Blomberg, David; Brickmann, Kay; Kihlberg, Jan
Tetrahedron, 2006 , vol. 62, # 47 p. 10937 - 10944
反应条件
sodium tetrahydroborate in methanol 5 h; 0 deg C -> r.t.;
参考文献
Reddy, G. Vidyasagar; Rao, G. Venkat; Iyengar
Tetrahedron Letters, 1999 , vol. 40, # 13 p. 2653 - 2656
