反应条件
1: B(OH)3, (EtO)3B / Heating
2: 1.) Et3N, 2.) Et3N, water / 1.) diethyl ether, RT, 5 h, 2.) diethyl ether, reflux, 2 h
3: CHCl3; propan-2-ol; dimethylformamide / 12 h / 50 °C
4: H2 / 10percent Pd/C / ethanol / 12 h / 40 °C / 1034.3 Torr
5: Et3N / CHCl3 / 24 h / Heating
View Scheme
参考文献
Godfroid, Jean-Jacques; Broquet, Colette; Jouquey, Simone; Lebbar, Mariya; Heymans, Francoise; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 5 p. 792 - 797
