2-氨基-4-甲基嘧啶-5-羧酸乙酯合成路线 （共 10 条）
反应条件
ammonia in tetrahydrofuran T=20°C; 0.75 h;
参考文献
Singh, Kamaljit; Singh, Kawaljit; Wan, Baojie; Franzblau, Scott; Chibale, Kelly; Balzarini, Jan
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 6 p. 2290 - 2294
反应条件
sodium ethanolate in ethanol 1 h; Heating;
参考文献
Schenone, Pietro; Sansebastiano, Laura; Mosti, Luisa
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 2 p. 295 - 305
反应条件
1: 1-methylguanidine hydrochloride With sodium ethanolate 0.5 h; 2: ethyl ethoxymethyleneacetoacetate 1 h; Heating;
参考文献
Vardanyan, Ruben S.; Danagulyan, Gevork G.; Mkrtchyan, Armen D.; Hruby, Victor J.
Heterocyclic Communications, 2011 , vol. 17, # 3-4 p. 129 - 133
反应条件
1: pyridinium chlorochromate 2: trichlorophosphate / 0.5 h / 105 °C 3: ammonia / tetrahydrofuran / 0.75 h / 20 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 6 p. 2290 - 2294
反应条件
1: trichlorophosphate / 0.5 h / 105 °C 2: ammonia / tetrahydrofuran / 0.75 h / 20 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 6 p. 2290 - 2294
参考文献
Huaxue Xuebao, , vol. 23, p. 145,150
Scientia Sinica (English Edition), , vol. 6, p. 853
Chem.Abstr., , p. 14626
反应条件
1: ethanolic sodium ethylate 2: NH3 View Scheme
参考文献
Huaxue Xuebao, , vol. 23, p. 145,150
Scientia Sinica (English Edition), , vol. 6, p. 853
Chem.Abstr., , p. 14626
参考文献
Journal of the Indian Chemical Society, , vol. 2, p. 67
Chem. Zentralbl., , vol. 97, # I p. 118
反应条件
potassium hydroxide in methanol 5 h; Heating;
参考文献
Schenone, Pietro; Sansebastiano, Laura; Mosti, Luisa
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 2 p. 295 - 305
反应条件
1: 93 percent / KOH / methanol / 5 h / Heating 2: 83 percent / 2 h / Heating View Scheme
参考文献
Schenone, Pietro; Sansebastiano, Laura; Mosti, Luisa
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 2 p. 295 - 305
