sodium hydroxide in methanol 1.5 h; Ambient temperature;

1: triethylamine; trifluoroacetic anhydride / dichloromethane / 10 h / 0 - 20 °C / Inert atmosphere 2: hydroxylamine hydrochloride; potassium hydroxide / water; isopropyl alcohol / 60 °C View Scheme

triethylamine; trifluoroacetic anhydride in dichloromethane T=0 - 20°C; 10 h; Inert atmosphere;

hydrogen; 10 palladium on activated carbon in methanol 3 h;