potassium fluoride; 18-crown-6 ether in N,N-dimethyl-formamide T=70°C; hydrofluorination; 5 h;

tetrabutyl ammonium fluoride; water in tetrahydrofuran T=40°C; 3 h;

lithium aluminium tetrahydride in diethylene glycol dimethyl ether T=110 - 115°C;

1: 93 percent / pyridine / 0.17 h / 0 - 10 °C 2: 62 percent / KF, CuI / dimethylformamide / 10 h / 100 °C View Scheme

copper in acetonitrile T=60°C; 9 h; Inert atmosphere;

1: (trifluoromethyl)-trimethylsilane With copper(l) iodide; cesium fluoride in acetonitrile T=20°C; 0.5 h; Inert atmosphere; 2: With [Cu(MeCN)]4*CF3SO3 in acetonitrile T=20°C; 0.0166667 h; Inert atmosphere; 3: O-(4-chlorobenzyl)-S-methyl dithiocarbonate in acetonitrile T=20°C; 0.0333333 h; Inert atmosphereSonication; Kinetics;

sulfuryl dichloride; 2,2'-azo-bisisobutyronitrile in benzene T=40°C; Irradiationrelative rate const. to XC6H4CH2CF3 (X= H, m-F, m-CF3) ;correlation between log k and Brown's const.; the method of competing reaction;; Product distribution;