3-甲基-2,4-戊烷二酮合成路线 （共 94 条）
反应条件
potassium phosphate; copper(l) iodide in N,N-dimethyl-formamide
T=120°C; 36 h; Inert atmosphere;
参考文献
Cai, Shangjun; Wang, Fei; Xi, Chanjuan
Journal of Organic Chemistry, 2012 , vol. 77, # 5 p. 2331 - 2336
反应条件
dihydrogen peroxide; copper(l) chloride in water; butanone; tert-butyl alcohol
T=20°C; 12 h; Acidic conditions;
参考文献
Dichtl, Alexander; Seyfried, Martin; Schoening, Kai-Uwe
Synlett, 2008 , # 12 p. 1877 - 1881
反应条件
1: piperidine; ethanol
2: aqueous sulfuric acid
3: phosphoryl chloride / 210 °C
4: Raney nickel; sodium methylate / Hydrogenation
View Scheme
参考文献
Prelog et al.
Helvetica Chimica Acta, 1942 , vol. 25, p. 1654,1660
反应条件
phosphoric acid
T=90°C; 13 h;
参考文献
Wang, Chun-Xia; Sato, Yusuke; Kudo, Megumi; Nishizawa, Seiichi; Teramae, Norio
Chemistry - A European Journal, 2012 , vol. 18, # 31 p. 9481 - 9484
反应条件
oxygen; cerium(III) chloride in isopropyl alcohol
T=23°C; P=760 Torr; 16 h;
参考文献
Christoffers, Jens; Kauf, Thomas; Werner, Thomas; Roessle, Michael
European Journal of Organic Chemistry, 2006 , # 11 p. 2601 - 2608
反应条件
triethylamine in dichloromethane
12 h;
参考文献
Pedrosa, Rafael; Andres, Jose Maria; Manzano, Ruben; Perez-Lopez, Cesar
Tetrahedron Letters, 2013 , vol. 54, # 24 p. 3101 - 3104
反应条件
1: (i) Na, benzene, (ii) /BRN= 635772/
2: H2 / Pd-BaSO4 / acetone
View Scheme
参考文献
Kochetkov,N.K.; Gottikh,B.P.
J. Gen. Chem. USSR (Engl. Transl.), 1960 , vol. 30, p. 948 - 953,963 - 968
反应条件
hydrogenchloride in ethanol
85 h; Ambient temperature;
参考文献
Picquenard, Eric; Dizabo, Pierre
Canadian Journal of Chemistry, 1981 , vol. 59, p. 1270 - 1276
反应条件
1: 1.) t-BuOK / 1.) Me2SO, room temp., 2.) Me2SO, irradiation, room temp., 6 h
2: 70 percent / lithium salt of 2-nitropropane / hexamethylphosphoric acid triamide / 5 h / Ambient temperature; Irradiation
View Scheme
参考文献
Ono, Noboru; Tamura, Rui; Eto, Hiromichi; Hamamoto, Isami; Nakatsuka, Tamon; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3678 - 3684
反应条件
acetic acid in ethanol
1) reflux, 2) RT;
参考文献
Singh, S. P.; Kodali, Dharma R.; Dhindsa, G. S.; Sawhney, S. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 1 p. 30 - 33
