反应条件
1: (6aR,9R,10aR)-7-allyl-N-[3-(dimethylamino)propyl]-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide With trimethylsilyl trifluoromethanesulfonate; triethylamine in dichloromethane T=-2 - 18°C; 14 h; 2: ethyl-isocyanate in dichloromethane T=18°C; 48 h; 3: With tetrabutyl ammonium fluoride in tetrahydrofuran; dichloromethane T=-2°C; 4 h;
参考文献
Gutman, Arie; Tishin, Boris; Vilenski, Alex; Agazade, Albay; Pertzikov, Boris; Nisnevich, Gennady
Patent: US2004/209910 A1, 2004 ;
Location in patent: Page 8-9 ;
