3-氯-2,2-二(氯甲基)丙-1-醇合成路线 (共 14 条)
反应条件
phosphorus pentachloride T=150°C;
参考文献
Kuznetsov,E.V.; Vlasova,L.A.
J. Gen. Chem. USSR (Engl. Transl.), 1969 , vol. 39, p. 698 - 700,662 - 664
反应条件
potassium hydroxide in ethanol 72 h; Heating / reflux;
参考文献
Wyeth
Patent: US2005/282826 A1, 2005 ;
Location in patent: Page/Page column 28-29 ;
参考文献
Kutscher; Nagel
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1956 , vol. 303, p. 230
参考文献
Bartholomew; Stocks
Tetrahedron Letters, 1991 , vol. 32, # 36 p. 4795 - 4798
参考文献
Mooradian; Cloke
Journal of the American Chemical Society, 1945 , vol. 67, p. 943
反应条件
pyridine; thionyl chloride
参考文献
Raguse, Burkhard; Ridley, Damon D.
Australian Journal of Chemistry, 1988 , vol. 41, # 12 p. 1953 - 1962
反应条件
hydrogenchloride
T=185°C;
参考文献
Govaert; Beyaert
Mededelingen van de Koninklijke Vlaamse Academie voor Wetenschappen, Letteren en Schone Kunsten van Belgie, Klasse der Wetenschappen, 1940 , vol. 2, # 5 p. 3,16
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Urry; Eiszner
Journal of the American Chemical Society, 1952 , vol. 74, p. 5822,5825
反应条件
pyridine; thionyl chloride
T=120 - 130°C; Yield given. Yields of byproduct given;
参考文献
Lynch, Kathleen Mondanaro; Dailey, William P.
Journal of Organic Chemistry, 1995 , vol. 60, # 14 p. 4666 - 4668
参考文献
Degussa
Patent: US2835709 , 1955 ;