5’-O-(4,4’-二甲氧基三苯甲基)尿苷合成路线 （共 15 条）
反应条件
1: 31 percent / 2,6-lutidine / tetrahydrofuran / 0.33 h / 0 °C View Scheme
参考文献
Ozaki, Hiroaki; Nakamoto, Akio; Shimidzu, Takeo
Chemistry Letters, 1990 , # 6 p. 959 - 962
反应条件
1: 1) pyridine / 1) 0 to 5 deg C, 1h, 2a) 0 to 5 deg C, 1h, 2b) RT, 2h 2: 84 percent / KOH, NaBH4 / methanol / 23 h / Ambient temperature 3: 92 percent / pyridine / 2.75 h / Ambient temperature 4: 89 percent / NaN3 / dimethylformamide / 3 h / 110 - 115 °C 5: 80 percent / HOAc / H2O / 3 h / Ambient temperature View Scheme
参考文献
Kawana, Masajiro; Kuzuhara, Hiroyoshi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 4 p. 469 - 478
反应条件
(2R,4S)-3-((R)-cyclopentyl(1-methyl-1H-imidazol-2-yl)methyl)-4-isopropyl-2-methoxyoxazolidine; N,N-diisopropylethylamine hydrochloride; N-ethyl-N,N-diisopropylamine in tetrahydrofuran
T=20°C; 24 h; Inert atmosphere; Reagent/catalystConcentration;
参考文献
Sun, Xixi; Lee, Hyelee; Lee, Sunggi; Tan, Kian L.
Nature Chemistry, 2013 , vol. 5, # 9 p. 790 - 795
反应条件
silver perchlorate; 1,4-diaza-bicyclo[2.2.2]octane in tetrahydrofuran
T=20°C; 2 h;
参考文献
Hakimelahi, Gholam H.; Proba, Zbigniew A.; Ogilvie, Kelvin K.
Tetrahedron Letters, 1981 , vol. 22, # 52 p. 5243 - 5246
反应条件
pyridine in tetrahydrofuran
Ambient temperaturevar. ribonucleosides; Product distribution;
参考文献
Hakimelahi, Gholam H.; Proba, Zbigniew A.; Ogilvie, Kelvin K.
Tetrahedron Letters, 1981 , vol. 22, # 48 p. 4775 - 4778
