反应条件
1: 1.) p-toluenosulfonic acid, 2.) H2 / 2.) PtO2 / 1.) toluene, reflux, 21 h, 2.) ethanol, 50 psi, 24 h
2: 69 percent / 48percent aq. HBr / 2 h / 120 °C
View Scheme
参考文献
Arvidsson; Hacksell; Johansson; Nilsson; Lindberg; Sanchez; Wikstroem; Svensson; Hjorth; Carlsson
Journal of Medicinal Chemistry, 1984 , vol. 27, # 1 p. 45 - 51
